Conversation with Merlin [email protected] · Thu Nov 02 2023

How does the human immune system work?

Here is a brief overview of how the human immune system works:

  • The immune system is made up of cells, tissues, and organs that work together to defend the body against infection.

  • The main components are white blood cells (lymphocytes and phagocytes), the spleen, thymus gland, lymph nodes, bone marrow, and lymphatic system.

  • There are two main branches - innate immunity and adaptive immunity. Innate immunity provides immediate defense but no memory. Adaptive immunity has specificity and memory.

  • Innate immunity involves physical and chemical barriers like skin, mucus, stomach acid, etc. It includes phagocytes that engulf pathogens.

  • Adaptive immunity involves B cells that produce antibodies, and T cells that directly attack infected cells. Antibodies target specific pathogens for destruction.

  • Antigen presenting cells display foreign pathogen pieces to T cells to trigger an immune response. Memory T and B cells remain after infection to provide faster response if the pathogen is encountered again.

  • The immune response is regulated by cytokines and other signaling molecules to balance protection with avoiding autoimmunity.