Conversation with Merlin [email protected] · Wed Dec 27 2023

find out sample size when prevalence between 0.5 to 1.5%

To calculate the sample size for a given prevalence, you can use the following formula:

[ n = \frac{{Z^2 \ p \times (1 - p)}}{{E^2 ]

Where:

  • ( n ) = sample size
  • ( Z \ = Z-score, which corresponds to the desired level of confidence (e.g., 1.96 for 95% confidence)
  • ( p ) = estimated prevalence as a decimal (e.g., 0.005 for0.5% and 0.015 for 1.5%)
  • ( E ) = margin of error as a decimal

Let's assume we want a level of 95% (which corresponds to a Z-score of 196) and a margin of error of 5% (.05). Plugging these values into the formula for the given prevalence range:

For 0.5% prevalence: [ n = {{1.96^2 \times 0.005 \times (1 - 0.005)}}{{0.05^2}} ] [ n \approx 753 ]

For 1.5% prevalence: [ n = \frac{{1.96^2 \times 0.015 \times (1 0.015)}}{{0.05^2}} ] [ napprox 254 ]

So, to achieve a 95% confidence level with a % margin of error, you would need a sample size of approximately 753 for a prevalence of 05% and 254 for a prevalence of 1.%.